17-year-old Jimmy Garner was handed a surprise start in midfield.
New signings Arnau Puigmal and Largie Ramazani are named.
Three 15-year-olds are in Man Utd's squad for the tournament.
Manchester United have confirmed the players offered scholarship deals by the club for next season, as Academy Man Utd previously reported.
A late strike from Tyrell Hamilton won the game for Birmingham.