Tuanzebe has a new chant at Villa, and Fosu-Mensah in action at a Premier League club.
Cameron Borthwick-Jackson, Regan Poole, Devonte Redmond and Matty Willock were all unused.
DJ Buffonge made and scored a goal as Man Utd's under-23s came from behind in a friendly at Bradford City's training ground.
Goals from Gribbin and Scott earned United a friendly draw at Moor Lane against National League opposition.
Dean Henderson is still looking for a first Grimsby Town appearance while Andreas Pereira faces former-United man Nani's Valencia.